Buy Tripeptide-29 (200mg) – Premium Collagen Peptide for Research

Welcome to Liaocheng Yixin Company, your trusted source for premium tripeptide-29 200mg for research. As a licensed peptide synthesis manufacturer operating from our facility in Shandong Province, China, we provide high-quality research compounds for the global scientific community.

Tripeptide-29, also known as Gly-Pro-Hyp (GPH) or Glycylprolylhydroxyproline, is a collagen-derived tripeptide that serves as the most fundamental and stable tripeptide unit in the collagen triple helix . As a key marker of collagen metabolism and a potent signaling molecule, it has emerged as a compound of high interest in dermatological, regenerative, and extracellular matrix research. Our tripeptide-29 200mg for research offers a reliable, high-purity compound for fibroblast activation, collagen synthesis, and signaling pathway investigations. tripeptide-29 200mg for research

What is Tripeptide-29?

Tripeptide-29 is a synthetic, highly purified peptide consisting of the amino acids glycine and proline plus the amino acid derivative hydroxyproline . It is also known by the CAS number 2239-67-0 and has a molecular weight of 285.30 g/mol . Its small molecular size (below 500 Da) allows it to easily penetrate skin’s upper layers so it can reach its target areas .

Key identifiers:

• CAS Number: 2239-67-0

• Molecular Formula: C₁₂H₁₉N₃O₅

• Molecular Weight: 285.30 g/mol

• Sequence: H-Gly-Pro-Hyp-OH

• Synonyms: Glycylprolylhydroxyproline, GPH, Tripeptide-29

• Purity: ≥99% verified by HPLC

• tripeptide-29 200mg for research

Mechanism of Action in Research

Tripeptide-29 (Gly-Pro-Hyp) operates through several well-characterized mechanisms that make it a valuable research tool for collagen metabolism and cell signaling studies.

Collagen Synthesis Activation

Tripeptide-29 binds to specific cell surface receptors and initiates intracellular signaling cascades. Research demonstrates that it stimulates collagen synthesis through fibroblast receptor binding, significantly increasing type I collagen production . In vitro studies have shown that Tripeptide-29 can increase type I and type III collagen synthesis by 42% through activation of the TGF-β signaling pathway .

Anti-inflammatory Signaling

Tripeptide-29 has been suggested to regulate the TNF and IL-17 signaling pathways through modulation of the AP-1 transcription factor complex . This regulates the expression of pro-inflammatory cytokines such as TNF-α and IL-17, thereby exerting anti-inflammatory effects .

Matrix Metalloproteinase (MMP) Inhibition

Tripeptide-29 inhibits MMP-1 activity, reducing UV-induced collagen degradation . This dual-action mechanism—stimulating new collagen synthesis while protecting existing collagen from breakdown—makes it a valuable research tool for studying extracellular matrix dynamics.

Skin Barrier Support

Tripeptide-29 enhances ceramide synthase activity in the stratum corneum, improving skin hydration and barrier function . It has been shown to increase skin hydration by 23% in clinical evaluations .

Research Applications

Fibroblast and Collagen Research

Tripeptide-29 is used to study fibroblast activation, collagen synthesis pathways, and extracellular matrix remodeling. In vitro tests have confirmed its efficacy in stimulating collagen production and fibroblast proliferation .

Dermatological and Aging Research

A four-week clinical study of 47 women aged 36-65 demonstrated significant improvements: 72.5% hydration increase at 15 minutes post-application, 32.7% improvement in wrinkle score at Week 4, and 20.5% improvement in forehead wrinkle score at Week 4 .tripeptide-29 200mg for research

Anti-inflammatory Pathway Studies

Researchers use Tripeptide-29 to investigate inflammatory signaling pathways, including TNF, IL-17, and AP-1 transcription factor modulation .

Formulation and Delivery Research

Tripeptide-29’s small size and high purity make it suitable for formulation science research. Typical usage levels range from 0.1% to 1% .

Why Choose Liaocheng Yixin Company?

When you buy tripeptide-29 200mg for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC and mass spectrometry. Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥99% verified by HPLC

• CAS Number: 2239-67-0

• Molecular Weight: 285.30 g/mol

• Sequence: H-Gly-Pro-Hyp-OH

• tripeptide-29 200mg for research

• Appearance: White to off-white lyophilized powder

• Storage: Store powder at -20°C in a sealed, desiccated container, protected from light and moisture. Keep away from moisture .

• Form: Lyophilized powder for research use

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification

4. Mass Spectrometry for molecular weight confirmation

5. Packaged under sterile conditions for research use

6. tripeptide-29 200mg for research

: What is Tripeptide-29 and how does it work in research?

A: Tripeptide-29 (Gly-Pro-Hyp) is a collagen-derived tripeptide that serves as a key signaling molecule in collagen metabolism. It stimulates collagen synthesis through fibroblast receptor activation, regulates inflammatory pathways including TNF and IL-17 signaling, and inhibits MMP-1 activity .

: What are the key research applications for Tripeptide-29?

A: Tripeptide-29 is used in fibroblast and collagen research, dermatological and aging studies, anti-inflammatory pathway investigations, and formulation/delivery research. It has been shown to improve collagen synthesis by up to 42% and reduce wrinkles by 32.7% in clinical studies .

: What purity level can I expect?

A: All batches are tested to ensure ≥99% purity by HPLC analysis. Certificates of Analysis are available upon request.

: Is this product for human use?

A: No. Our Tripeptide-29 is manufactured strictly for research use only (RUO). It is not intended for human consumption or clinical applications.

When you need premium tripeptide-29 200mg for research for your fibroblast, collagen, or extracellular matrix studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust.