Buy Survodutide – Premium Research Dual Agonist Peptide

Welcome to Liaocheng Yixin Company, your trusted source for premium survodutide peptide for research. As a licensed peptide synthesis manufacturer operating from our facility in Shandong Province, China, we provide high-quality research compounds for the global scientific community.

Survodutide (BI 456906) is a synthetic 29-amino-acid peptide designed as a dual agonist targeting both the glucagon receptor (GCGR) and the glucagon-like peptide-1 receptor (GLP-1R). This dual mechanism of action distinguishes it from single-receptor agonists and has made it a focal point in metabolic disease research. When you buy survodutide for research, you gain access to a well-characterized tool for advancing studies in obesity, metabolism, and metabolic dysfunction-associated steatohepatitis.  survodutide peptide for research

What is Survodutide?

Survodutide is a long-acting acylated peptide that incorporates structural modifications to the human glucagon sequence, including a non-coded amino acid (1-aminocyclobutane-1-carboxylic acid) at position 2 to enhance proteolytic stability and a C18 fatty acid moiety to prolong half-life through albumin binding. Its molecular formula is C192H289N47O61 with a molecular weight of approximately 4231.63 g/mol.

Key identifiers:

• CAS Number: 2805997-46-8

• Molecular Weight: ~4231.63 g/mol

• Sequence: 29-amino-acid peptide

• Synonyms: BI 456906

• Purity: ≥98% verified by HPLC

• survodutide peptide for research

Mechanism of Action in Research

Survodutide exerts its effects through balanced dual receptor engagement:

GLP-1 Receptor Agonism
Survodutide activates the GLP-1 receptor, providing well-established benefits on appetite suppression and glycemic control. In GLP-1 receptor knockout mice, survodutide did not reduce food intake or improve glucose tolerance, confirming that these acute metabolic effects are driven by GLP-1R interaction.

Glucagon Receptor (GCGR) Agonism
The glucagon receptor component is hypothesized to contribute to energy expenditure and fat metabolism, offering additional metabolic benefits beyond weight loss.

Metabolic Signaling
Survodutide influences multiple metabolic pathways including regulation of insulin and glucagon secretion, inhibition of food intake, and modulation of gastric emptying. It has been associated with significant improvements in beta-cell function and insulin sensitivity that are largely independent of bodyweight changes.

Scientific Research Applications

Survodutide has been studied across multiple research domains with promising results:

Obesity and Weight Management Research
In Phase 2 trials, participants who reached the 4.8 mg dose achieved a mean body weight loss of 18.7% at 46 weeks. Phase 3 data (SYNCHRONIZE-1, April 2026) demonstrated 16.6% average weight loss at 76 weeks compared to 3.2% on placebo, with the majority of loss coming from fat tissue.

Metabolic and Beta-Cell Function Research
Survodutide has been shown to improve biomarkers of beta-cell function (HOMA-β) and insulin sensitivity (HOMA-IR) in adults with type 2 diabetes or overweight/obesity. These effects were found to be largely independent of bodyweight changes, suggesting additional metabolic benefits beyond weight loss.

MASH and Liver Disease Research
Survodutide has received Breakthrough Therapy designation for MASH based on strong Phase 2 results, making it relevant for research into metabolic dysfunction-associated steatohepatitis.

Insulin Sensitivity Studies
Phase 2 studies showed survodutide was associated with significant decreases in HOMA-IR, glucagon, C-peptide, fasting insulin, and fasting plasma glucose in participants with overweight/obesity.  survodutide peptide for research

Why Choose Liaocheng Yixin Company?

When you buy survodutide peptide for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards and follows rigorous synthetic protocols for all peptides, including Survodutide.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC analysis. Our Survodutide meets ≥98% purity standards. Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥98% verified by HPLC

• Molecular Weight: ~4231.63 g/mol

• CAS Number: 2805997-46-8

• Appearance: Lyophilized powder

• Storage: Store powder at -20°C in a sealed, desiccated container, protected from light and moisture

• Form: Lyophilized powder for research use

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification (>98%)

4. Mass Spectrometry for molecular weight confirmation

5. Packaged under sterile conditions for research use

6. survodutide peptide for research

When you need premium survodutide peptide for research for your obesity, metabolic, or MASH studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust.