Cartalax (20mg) – Premium Tripeptide Bioregulator for Cartilage Research

Welcome to Liaocheng Yixin Company, your trusted source for premium cartalax 20mg peptide for research. As a specialized peptide synthesis manufacturer operating from our facility at No. 9 Lushan Road, Dongcheng Street, Liaocheng Economic and Technological Development Zone, Shandong Province, we provide high-quality research compounds for the global scientific community.

Cartalax is a synthetic tripeptide bioregulator with the amino acid sequence Ala-Glu-Asp (AED) . It was developed as part of the Khavinson peptide family at the St. Petersburg Institute of Bioregulation and Gerontology and is specifically designed to target cartilage and connective tissue . Its structural alignment with sequences found in the alpha-1 chain of type XI collagen suggests potential interactions with extracellular matrix components . Our cartalax 20mg peptide for research offers investigators a reliable, high-purity compound for cartilage biology, chondrocyte function, and tissue regeneration studies.

What is Cartalax?

Cartalax is a short-chain synthetic peptide composed of alanine, glutamic acid, and aspartic acid, with the one-letter code AED . It belongs to a class of peptide bioregulators studied for their ability to influence tissue-specific gene expression, particularly in cartilage and connective tissue experimental systems .

Key identifiers:

• CAS Number: 3918-52-9 

• Molecular Formula: C12H19N3O8 

• Molecular Weight: 333.30 g/mol 

• Sequence: Ala-Glu-Asp (AED)

• Synonyms: T-31 peptide, Ala-Glu-Asp, Cartalax peptide, Khavinson peptide

• Purity: ≥99% verified by HPLC 

Mechanism of Action in Researccartalax 20mg peptide for researchh

Cartalax exerts its biological effects through several distinct mechanisms that make it a valuable tool for cartilage and connective tissue research:

DNA-Promoter Interactions and Gene Regulation

Research within the Khavinson model suggests the AED motif can interact with specific DNA promoter sites . Cartalax is studied as a candidate transcriptional regulator, with molecular docking work indicating it may bind to specific sequences in the DNA minor groove to influence gene expression . This sequence-specific binding may impact local chromatin conformation and, in turn, influence the transcription of genes linked to cell aging and tissue maintenance .

Chondrocyte and Fibroblast Modulation

In chondrocyte and fibroblast cultures, Cartalax has been used to examine effects on cell proliferation, apoptosis, and expression of extracellular-matrix genes . Research demonstrates that Cartalax:

• Increases Ki-67 expression in fibroblast cultures, indicating enhanced cell proliferation 

• Reduces caspase-3 expression, suggesting decreased apoptotic signaling 

• Inhibits matrix metalloproteinase-9 (MMP-9) activity, which is linked to extracellular matrix degradation 

• Modulates senescence markers including p16, p21, and p53 

• cartalax 20mg peptide for research

Cellular Aging Pathways

Cartalax has been studied for its potential to modulate markers associated with cellular senescence. Research indicates it may reduce expression of p16, p21, and p53—proteins commonly associated with cell cycle regulation and senescence—while increasing SIRT-6, a sirtuin linked to longevity and genomic stability .

Scientific Research Applications

Cartalax has been studied across multiple research domains:

Cartilage and Connective Tissue Research

Cartalax is frequently utilized in studies focused on cartilage biochemistry and tissue remodeling . Its ability to interact with chondrocytes and associated matrix molecules makes it a useful tool for examining the synthesis and turnover of proteoglycans, collagen, and other key structural proteins . Research demonstrates that Cartalax regulates chondrogenic differentiation pathways including WNT, ERK-p38, and Smad 1/5/8 signaling, promoting expression of cartilage-specific proteins COL2, SOX9, and ACAN in mesenchymal stem cells .cartalax 20mg peptide for research

Cell Renewal and Anti-Aging Research

In aging renal epithelial cell cultures, Cartalax has been shown to diminish expression of p53, a pro-apoptotic transcription factor, potentially creating conditions that favor cell renewal . Research suggests the peptide may upregulate SIRT-6, which is correlated with cellular longevity .

Extracellular Matrix Studies

In fibroblast cultures, Cartalax has been shown to stimulate collagen type I and sirtuin production while modulating inflammatory markers . Its potential to diminish MMP-9 expression hints at a possible reduction in excessive extracellular matrix breakdown .

Connective Tissue Aging Research

Cartalax is studied in the context of age-related musculoskeletal changes, examining its effects on extracellular matrix maintenance and tissue regeneration capacity in aging models .

Why Choose Liaocheng Yixin Company?

When sourcing cartalax 20mg peptide for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC analysis. Our Cartalax meets ≥99% purity standards . Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥99% verified by HPLC

• Appearance: White to off-white lyophilized powder 

• Molecular Weight: 333.30 g/mol

• Solubility: Soluble in water and buffered aqueous solutions 

• Storage: Store powder at -20°C in a sealed, desiccated container, protected from light and moisture 

• Form: Lyophilized powder for research use

• cartalax 20mg peptide for research

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification (≥99%)

4. Mass Spectrometry for molecular weight confirmation

5. Packaged in sterile conditions for research use

6. cartalax 20mg peptide for research

: What is Cartalax and how does it work in research?

A: Cartalax is a synthetic tripeptide (Ala-Glu-Asp) that functions as a cartilage and connective tissue bioregulator . It is studied for its ability to regulate gene expression in chondrocytes and fibroblasts, potentially influencing cell proliferation, apoptosis, and extracellular matrix synthesis .

: What are the key research applications for Cartalax?

A: Cartalax is used in cartilage and connective tissue research, cell renewal and anti-aging studies, extracellular matrix research, and musculoskeletal aging investigations .

: How does Cartalax relate to Epithalon?

A: Both are Khavinson bioregulatory peptides with overlapping sequences. Epithalon (Ala-Glu-Asp-Gly) contains the full Cartalax sequence (Ala-Glu-Asp) plus an additional glycine residue. However, they target different organ systems—Cartalax focuses on cartilage while Epithalon targets the pineal gland .

: What purity level can I expect?

A: All batches are tested to ensure ≥99% purity by HPLC analysis. Certificates of Analysis are available upon request.

: Is this product for human use?

A: No. Our Cartalax is manufactured strictly for research use only (RUO). It is not intended for human consumption or clinical applications .

When you need premium cartalax 20mg peptide for research for your cartilage biology, chondrocyte function, or connective tissue studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust.