Chonluten (20mg) – Premium EDG Tripeptide for Research

Welcome to Liaocheng Yixin Company, your trusted source for premium chonluten 20mg peptide for research. As a specialized peptide synthesis manufacturer operating from our facility at No. 9 Lushan Road, Dongcheng Street, Liaocheng Economic and Technological Development Zone, Shandong Province, we provide high-quality research compounds for the global scientific community. chonluten 20mg peptide for research

Chonluten (also known as T-34 or EDG) is a synthetic tripeptide bioregulator composed of glutamic acid, aspartic acid, and glycine, with the sequence Glu-Asp-Gly . It belongs to the Khavinson peptide family—bioregulators initially isolated from animal tissues and characterized by their tissue-specific effects . Research suggests that Chonluten’s small size allows it to interact with genomic regulatory regions, potentially influencing the expression of genes involved in antioxidant pathways, stress response, and inflammatory mediators . Our chonluten 20mg peptide for research offers investigators a reliable, high-purity compound for respiratory, mucosal, and gene expression studies.

What is Chonluten?

Chonluten is a tripeptide with the amino acid sequence Glu-Asp-Gly (EDG). It was developed within the Khavinson bioregulator framework at the St. Petersburg Institute of Bioregulation and Gerontology . The peptide has been studied primarily for its potential to regulate stress-response genes, antioxidant enzymes, and inflammatory mediators .

Key identifiers:

• CAS Number: Not specified in search results

• Molecular Formula: C11H17N3O8 

• Molecular Weight: 319.27 g/mol 

• Sequence: Glu-Asp-Gly (EDG) 

• Synonyms: T-34, EDG peptide, Chonluten®

• Purity: ≥99% verified by HPLC

• chonluten 20mg peptide for research

Mechanism of Action in Research

Chonluten’s proposed mechanisms are the subject of ongoing investigation in molecular biology research.

Gene Expression Modulation

Research indicates that Chonluten may bind to DNA promoter or suppressor sequences, or indirectly influence epigenetic markers such as DNA methylation, modulating the expression of genes associated with antioxidant pathways, stress response proteins, structural maintenance, and inflammatory mediators . The peptide may fine-tune the synthesis of proteins like superoxide dismutase (SOD), heat shock protein 70 (HSP70), COX-2, TNF-α, and c-Fos, supporting transcriptional programs that govern cellular stress, survival, and structural integrity . chonluten 20mg peptide for research

Anti-Inflammatory Activity

A 2022 study published in the International Journal of Molecular Sciences evaluated Chonluten’s effects on the THP-1 monocyte/macrophage cell line . Key findings included:

• Inhibition of TNF production in monocytes exposed to pro-inflammatory bacterial lipopolysaccharide (LPS) 

• Reduced expression of pro-inflammatory IL-6 stimulated by LPS 

• Reduced cell adhesion to activated endothelial cells, a typical pro-inflammatory mechanism 

The study suggested that Khavinson peptides, including Chonluten, cooperate as natural inducers of TNF tolerance in monocytes and act as anti-inflammatory molecules during inflammatory and microbial-mediated activity .

Respiratory and Mucosal Tissue Focus

Chonluten has been primarily studied in the context of respiratory mucosal tissue and lung epithelial cell function . Its tissue specificity is believed to derive from its sequence—the EDG core directs it toward bronchial and mucosal tissues .

Molecular Profile

The tripeptide consists of three non-essential amino acids: glutamic acid, aspartic acid, and glycine. Its diminutive size is believed to allow penetration of cellular and nuclear membranes, potentially enabling direct interaction with genomic regulatory regions .

Scientific Research Applications

Chonluten has been studied across several research domains, though the published record is limited compared to other peptides :

Inflammatory Pathway Research

Chonluten is studied for its capacity to modulate inflammatory signaling in macrophages and monocytes. Research demonstrates inhibition of TNF and IL-6 expression in LPS-stimulated cells . This makes Chonluten a potential tool for investigating anti-inflammatory mechanisms in immune cell models.

Respiratory and Mucosal Research

Investigations suggest Chonluten may support the normalization of redox and inflammatory gene markers in respiratory epithelial models . Research has explored its potential role in mucosal barrier function and respiratory epithelial health .

Gene Expression and Stress Response Research

Chonluten is used to study the regulation of stress-response genes including HSP70, c-Fos, COX-2, and TNF-alpha . Its potential to modulate antioxidant enzymes like SOD makes it relevant for oxidative stress research .

Connective Tissue and ECM Research

The peptide’s potential to promote collagen synthesis and extracellular matrix remodeling is being explored in wound healing and tissue repair models .

Why Choose Liaocheng Yixin Company?

When sourcing chonluten 20mg peptide for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC analysis. Our Chonluten meets ≥99% purity standards. Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥99% verified by HPLC

• Molecular Weight: 319.27 g/mol 

• Sequence: Glu-Asp-Gly (EDG)

• Appearance: White to off-white lyophilized powder

• Storage: Store powder at -20°C in a sealed, desiccated container, protected from light and moisture

• Form: Lyophilized powder for research use

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification

4. Mass Spectrometry for molecular weight confirmation

5. Packaged in sterile conditions for research use

6. chonluten 20mg peptide for research

: What is Chonluten and how does it work in research?

A: Chonluten is a synthetic tripeptide (Glu-Asp-Gly) belonging to the Khavinson bioregulator family . It is studied for its potential to modulate gene expression, particularly genes involved in antioxidant pathways, stress response (HSP70, c-Fos), and inflammatory mediators (TNF-α, COX-2) .

: What is the published research on Chonluten?

A: Based on available data, one primary published study exists on Chonluten: a 2022 non-human in vitro study in the International Journal of Molecular Sciences demonstrating that the peptide modulates proliferative activity and inflammatory pathways in THP-1 monocyte/macrophage cells . No human clinical trials have been conducted .

: What are the key research applications for Chonluten?

A: Chonluten is used in inflammatory pathway research, respiratory and mucosal tissue studies, gene expression and stress response investigations, and extracellular matrix research .

: What purity level can I expect?

A: All batches are tested to ensure ≥99% purity by HPLC analysis. Certificates of Analysis are available upon request.

: Is this product for human use?

A: No. Our Chonluten is manufactured strictly for research use only (RUO). It is not intended for human consumption or clinical applications.

When you need premium chonluten 20mg peptide for research for your inflammatory pathway, respiratory, or gene expression studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust.