HGH Fragment 176-191 (5mg) – Premium Research Peptide for Metabolic Studies

Welcome to Liaocheng Yixin Company, your trusted source for premium hgh fragment 176-191 5mg for research. As a specialized peptide synthesis manufacturer operating from our facility at No. 9 Lushan Road, Dongcheng Street, Liaocheng Economic and Technological Development Zone, Shandong Province, we provide high-quality research compounds for the global scientific community.hgh fragment 176-191 5mg for research

HGH Fragment 176-191 is a synthetic peptide corresponding to the C-terminal region of the human growth hormone (hGH) molecule. This 16-amino-acid fragment has garnered attention in metabolic and regenerative research for its potential to influence lipid metabolism without the systemic hormonal effects associated with full-length growth hormone. Our hgh fragment 176-191 5mg for research offers investigators a reliable, high-purity compound for metabolic, cancer, and tissue repair studies.

What is HGH Fragment 176-191?

HGH Fragment 176-191 (CAS: 66004-57-7) is a synthetic peptide consisting of the final 16 amino acids of human growth hormone, specifically residues 176 through 191. It is also known as AOD-9604 when modified with an additional tyrosine residue at the N-terminus .

Key identifiers:

• CAS Number: 66004-57-7 (free base) 

• Molecular Formula: C78H125N23O23S2

• Molecular Weight: 1815.09 g/mol 

• hgh fragment 176-191 5mg for research

• Sequence: H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH (Disulfide bridge Cys7-Cys14) 

• Length: 16 amino acids

• Synonyms: HGH Frag 176-191, AOD-9604, Human growth hormone fragment

• Purity: ≥99% verified by HPLC

Mechanism of Action in Research

Lipid Metabolism Pathway

HGH Fragment 176-191 is hypothesized to influence fat metabolism through selective targeting of lipolytic pathways . Research suggests the peptide may promote lipolysis (the breakdown of fat) while inhibiting lipogenesis (the formation of new fat deposits) .

Selective Activity Profile

Unlike full-length hGH, Fragment 176-191 is believed to selectively target lipid metabolism pathways without significantly impacting insulin or IGF-1 levels . This selective profile makes it a valuable research tool for studying fat metabolism independently of the broader hormonal effects associated with growth hormone.

Receptor Binding Profile

Research has shown that HGH Fragment 176-191 binds with high affinity to Ki-67, MiB protein, and estrogen receptor . It does not activate GH receptors and was designed to minimize negative endocrine effects .hgh fragment 176-191 5mg for research

Scientific Research Applications

Metabolic and Fat Metabolism Research

Investigations purport that HGH Fragment 176-191 may promote lipolysis while inhibiting lipogenesis, processes critical for maintaining energy balance and metabolic homeostasis . A study published in the Journal of Endocrinology found that GH fragment 176-191 increased lipid oxidation in test systems and did not stimulate IGF-1 or GH signaling like full GH .

Cancer Research

A 2022 study published in Drug Design, Development and Therapy evaluated the anticancer efficacy of chitosan nanoparticles loaded with HGH Fragment 176-191 plus doxorubicin . The dual-loading strategy demonstrated greater anti-proliferative activity against the MCF-7 breast cancer cell line than doxorubicin alone .

Cartilage and Tissue Research

Some exploratory trials have studied the peptide’s potential role in cartilage regeneration, post-injury recovery, and inflammation modulation . Research indicates that AOD-9604 may influence chondrocyte activity and matrix synthesis .

Bone and Muscular Tissue Research

Emerging data suggests HGH Fragment 176-191 may impact pathways involved in bone remodeling and muscular tissue repair. The peptide is hypothesized to support the mineralization of bone tissue and promote satellite cell activation in muscle research .

Why Choose Liaocheng Yixin Company?

When sourcing hgh fragment 176-191 5mg for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC analysis. Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥99% verified by HPLC

• Appearance: White to off-white lyophilized powder

• Storage: Store powder at -20°C in a sealed container, protected from light and moisture 

• Form: Lyophilized powder for research use

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification

4. Mass Spectrometry for molecular weight confirmation

5. Packaged in sterile conditions for research use

6. hgh fragment 176-191 5mg for research

: What is the difference between HGH Fragment 176-191 and AOD-9604?

A: AOD-9604 is a modified version of HGH Fragment 176-191 with an additional tyrosine residue at the N-terminus, designed to support stability and activity . Both terms are often used interchangeably in research contexts.

: How does HGH Fragment 176-191 work in research?

A: Research suggests the peptide promotes lipolysis (fat breakdown) while inhibiting lipogenesis (fat formation), selectively targeting lipid metabolism pathways without affecting GH or IGF-1 signaling .

: What research applications use HGH Fragment 176-191?

A: The peptide is used in metabolic research (lipid metabolism, obesity studies), cancer research (breast cancer models), cartilage and tissue regeneration studies, and bone/muscle tissue research .

: What purity level can I expect?

A: All batches are tested to ensure ≥99% purity by HPLC analysis. Certificates of Analysis are available upon request.

: Is this product for human use?

A: No. Our HGH Fragment 176-191 is manufactured strictly for research use only (RUO). It is not intended for human consumption or clinical applications .

When you need premium hgh fragment 176-191 5mg for research for your metabolic, cancer, or tissue regeneration studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust. hgh fragment 176-191 5mg for research