GHRP-2 Acetate – Premium Research Peptide for Growth Hormone Studies

Welcome to Liaocheng Yixin Company, your trusted source for premium ghrp-2 acetate for research. As a specialized peptide synthesis manufacturer operating from our facility at No. 9 Lushan Road, Dongcheng Street, Liaocheng Economic and Technological Development Zone, Shandong Province, we provide high-quality research compounds for the global scientific community.

GHRP-2 (Pralmorelin) is a synthetic hexapeptide growth hormone-releasing peptide that acts on the hypothalamus and pituitary gland to stimulate growth hormone release . Our ghrp-2 acetate for research offers investigators a reliable, high-purity compound for endocrinology and growth hormone research applications.

What is GHRP-2 Acetate?

GHRP-2 Acetate (also known as Pralmorelin or KP-102) is a synthetic hexapeptide growth hormone secretagogue . It is considered a true hGH secretagogue, meaning it stimulates the body’s own secretion of growth hormone . GHRP-2 is an agonist of the growth hormone secretagogue receptor (GHS-R), also known as the ghrelin receptor .

Key identifiers:

• CAS Number: 158861-67-7 

• Molecular Formula: C45H55N9O6 

• Molecular Weight: 817.97 g/mol 

• Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 

• Synonyms: Pralmorelin, KP-102, GHRP-2 

• Purity: ≥99% verified by HPLC

Mechanism of Action in Research

GHRP-2 exerts its effects through binding to the growth hormone secretagogue receptor (GHS-R) in the hypothalamus and pituitary gland . This binding activates intracellular signaling pathways involving the production of cyclic adenosine monophosphate (cAMP) and the activation of protein kinase A (PKA). This cascade leads to the influx of calcium ions into pituitary cells, which is critical for the exocytosis of growth hormone-containing vesicles .

Key research observations:

• Growth hormone stimulation: GHRP-2 induces GH release from primary rat pituitary cells (EC50 = 1.8 nM) 

• Receptor binding: Binds to human hypothalamic membranes (IC50 = 16 nM) 

• In vivo activity: Increases blood GH levels in anesthetized rats (ED50 = 30 nmol/kg) 

• Serum GH response: Elevates serum GH levels in conscious pigs (ED50 = 0.6 nmol/kg) 

• Short half-life: Peak concentrations occur around 15 minutes and do not exceed 60 minutes after administration 

Scientific Research Applications

GHRP-2 has been studied across multiple research domains:

Endocrinology Research:

• Assessment of growth hormone deficiency (GHD) 

• Investigation of hypothalamic-pituitary axis function

• Studies on growth hormone secretion regulation

Anti-inflammatory Research:

• A study published in the American Journal of Physiology-Endocrinology and Metabolism demonstrated anti-inflammatory effects of GHRP-2 in arthritic rat models 

• Researchers observed modulation of inflammatory markers through ghrelin receptor agonism

Appetite and Metabolism Studies:

• GHRP-2 increases food intake and body weight gain in rats when administered at 100 μg/kg per day 

• Investigation into metabolic regulation pathways

Cancer Research:

• Studies have examined GHRP-2’s effects as an inhibitor of phosphogluconate dehydrogenase (PGD), a key enzyme in the pentose phosphate pathway 

Why Choose Liaocheng Yixin Company?

When sourcing ghrp-2 acetate for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC analysis. Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥99% verified by HPLC

• Appearance: White lyophilized powder 

• Storage: Store powder at -20°C in a sealed container, protected from light and moisture 

• Stability: Hygroscopic – protect from moisture 

• Form: Lyophilized powder for research use

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis (SPPS) 

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification 

4. Mass Spectrometry for molecular weight confirmation 

5. Packaged in sterile conditions for research use

When you need premium ghrp-2 acetate for research for your endocrinology, growth hormone, or metabolic studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust.