Ovagen (20mg) – Premium Research Tripeptide for Hepatic & GI Studies

Welcome to Liaocheng Yixin Company, your trusted source for premium ovagen 20mg for research. As a specialized peptide synthesis manufacturer operating from our facility in Shandong Province, China, we provide high-quality research compounds for the global scientific community.

Ovagen (also known as EDL, or the tripeptide sequence Glu-Asp-Leu) is a Khavinson bioregulator peptide designed to support hepatic and gastrointestinal tissue research . It is classified among the cytogen family of short peptide bioregulators, which are proposed to interact with DNA and chromatin structures to regulate gene expression . Our ovagen 20mg for research offers investigators a reliable, high-purity compound for liver function, GI mucosal health, and epigenetic regulation studies.

What is Ovagen?

Ovagen is a synthetic tripeptide bioregulator composed of three amino acids: glutamic acid, aspartic acid, and leucine (Glu-Asp-Leu) . It was developed by Russian scientist Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology as part of a broader program investigating tissue-specific peptide regulation .

Key Identifiers:

• CAS Number: 121062-08-6 

• Molecular Formula: C15H25N3O8 

• Molecular Weight: 375.38 g/mol 

• Sequence: Glu-Asp-Leu (EDL) 

• Purity: ≥99% verified by HPLC

Mechanism of Action in Research

Ovagen functions through epigenetic regulation mechanisms that are the subject of ongoing research:

Cellular Uptake & Transport

As a tripeptide, Ovagen is transported via POT family transporters (PEPT1, PEPT2) that specifically handle di- and tripeptides . PEPT1 is expressed at high levels in intestinal epithelium, while PEPT2 is found in the kidney, liver, and other tissues—potentially providing a tissue-targeting mechanism for hepatic delivery .

Gene Expression Modulation

Research suggests Ovagen can penetrate cell and nuclear membranes to interact directly with DNA and chromatin structures, modulating gene transcription patterns . In liver tissue specifically, studies have investigated effects on:

• Hepatocyte proliferation markers (Ki-67) and apoptosis regulators (p53) 

• Detoxification enzyme systems (cytochrome P450 family) 

• Anti-apoptotic factors in hepatocytes 

• Acute-phase protein synthesis 

Scientific Research Applications

Liver and GI Tissue Research

Ovagen is primarily studied for its effects on hepatic and gastrointestinal epithelial tissue . Research has explored its potential to:

• Modulate gene expression in hepatocyte cultures 

• Support liver regeneration and function in aging models 

• Protect GI mucosal integrity 

Epigenetic & Chromatin Studies

Ovagen serves as a reference compound for testing tissue-selective effects on proliferation/apoptosis markers (e.g. Ki-67, p53) in cultures derived from young versus aged tissue . This makes it valuable for investigating short-peptide chromatin interactions and transcriptional regulation .

Comparative Bioregulator Research

Within the Khavinson peptide bioregulator framework, Ovagen is often studied alongside other cytogen family members . It is sometimes combined with Livagen (KED) in research protocols exploring complementary liver-targeting bioregulators .

Why Choose Liaocheng Yixin Company?

When sourcing ovagen 20mg for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC analysis. Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥99% verified by HPLC 

• Appearance: White to off-white lyophilized powder 

• Solubility: Soluble in water and buffered aqueous solutions 

• Storage: Store powder at -20°C in a sealed container, protected from light and moisture 

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis 

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification

4. Mass Spectrometry for molecular weight confirmation

5. Packaged in sterile conditions for research use

When you need premium ovagen 20mg for research for your hepatic, gastrointestinal, or epigenetic studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust.