Vilon (20mg) – Premium Dipeptide Bioregulator for Research

Welcome to Liaocheng Yixin Company, your trusted source for premium vilon 20mg peptide for research. As a specialized peptide synthesis manufacturer operating from our facility at No. 9 Lushan Road, Dongcheng Street, Liaocheng Economic and Technological Development Zone, Shandong Province, we provide high-quality research compounds for the global scientific community.

Vilon is a synthetic dipeptide bioregulator composed of lysine and glutamic acid (Lys-Glu), and is recognized as one of the shortest peptides reported to show significant biological activity . It was developed within the Khavinson peptide framework at the St. Petersburg Institute of Bioregulation and Gerontology. Research indicates that Vilon functions at the chromatin level to modulate gene expression, reactivate silenced genes in aging cells, and support immune function . Our vilon 20mg peptide for research offers investigators a reliable, high-purity compound for chromatin biology, immunology, and epigenetic research.vilon 20mg peptide for research

What is Vilon?

Vilon is a synthetic dipeptide with the amino acid sequence Lys-Glu (KE). As a “minimal peptide” probe, it is frequently cited as the shortest peptide to demonstrate biological activity, making it a valuable reference for structure-activity studies .

Key Identifiers:

• CAS Number: 45234-02-4 

• Molecular Formula: C11H21N3O5

• Molecular Weight: 275.30 g/mol 

• Synonyms: KE, Lys-Glu, immune dipeptide bioregulator

• Purity: ≥99% verified by HPLC 

Mechanism of Action in Research

Vilon operates through mechanisms that are unique among peptide bioregulators, with research focusing on chromatin remodeling and gene expression regulation.

Chromatin Remodeling and Gene Reactivation

Research has shown that Vilon interacts directly with nuclear chromatin structure, promoting the unwrapping of facultative heterochromatin and reactivating previously silenced genomic regions . In cultured human lymphocytes, Vilon increases the proportion of transcriptionally active euchromatin and reactivates nucleolar organizer regions in cells from older donors, effectively reversing age-related chromatin condensation . This process is believed to be the mechanism by which Vilon may help restore protein synthesis in aging cells.vilon 20mg peptide for research

Immunomodulatory and Gene Expression Effects

Vilon has been demonstrated to modulate the expression of numerous genes involved in immune function, cell cycle regulation, and longevity pathways. Research has shown:

• Stimulation of IL-2 expression: A single intranasal administration of Vilon increased IL-2 mRNA gene expression in hypothalamic cells, indicating its ability to regulate gene expression in the central nervous system .

• Modulation of cardiac gene expression: Vilon changed expression of 36 clones in mouse heart studies, while combined with Epithalon modulated 144 clones .

• Thymocyte proliferation: Vilon stimulates the expression of argyrophilic proteins in nucleolar organizer regions of thymocytes, promoting ribosomal assembly, protein synthesis, and thymocyte transformation into proliferating blast cells .vilon 20mg peptide for research

• Anti-inflammatory activity: Studies on THP-1 monocytes demonstrated that Vilon inhibits the expression of TNF and pro-inflammatory IL-6 stimulated by LPS .

Geroprotective and Longevity Research

In CBA mice, Vilon administration increased maximum lifespan and reduced the incidence of spontaneous tumors by a factor of 1.5 . Incidences of lung adenoma and breast adenocarcinoma were reduced by a factor of 2.5, and the number of mice surviving to 23 months was 2.6 times higher than controls .

Scientific Research Applications

Vilon has been studied across multiple research domains:

Epigenetics and Chromatin Biology

• Investigating age-related chromatin condensation and gene silencing

• Studying reactivation of silenced genes in aging cells

• Chromatin remodeling and gene expression regulation

Immunology Research

• T-cell differentiation and thymic function studies

• Immune modulation in secondary immunodeficiency models

• Cytokine regulation (IL-2, TNF, IL-6 expression)

Aging and Longevity Research

• Geroprotective properties and lifespan extension studies

• Age-related thymic involution research

• Cellular senescence and functional decline

Gene Expression Studies

• Heart, immune, and central nervous system gene modulation

• DNA-microarray and gene expression profiling research

• “Minimal peptide” probe for structure-activity studies 

• vilon 20mg peptide for research

Why Choose Liaocheng Yixin Company?

When sourcing vilon 20mg peptide for research, quality and reliability are paramount. Here’s why researchers trust us:

Manufacturer-Direct Quality

We are a legitimate, licensed peptide synthesis company with a physical headquarters in Shandong Province, China. Our facility maintains strict quality control standards.

Verified Purity Standards

Every batch undergoes rigorous testing using HPLC analysis. Our Vilon meets ≥99% purity standards . Certificates of Analysis are available upon request.

Research-Grade Specifications

• Purity: ≥99% verified by HPLC

• Appearance: White to off-white lyophilized powder 

• Solubility: Soluble in water and buffered aqueous solutions

• Storage: Store powder at -20°C in a sealed, desiccated container, protected from light and moisture. Vilon is hygroscopic .

• Form: Lyophilized powder for research use

Quality Assurance & Testing

Every batch undergoes comprehensive quality control:

1. Synthesis by experienced chemists using solid-phase peptide synthesis

2. Purification via preparative HPLC

3. Analysis using HPLC for purity verification

4. Mass Spectrometry for molecular weight confirmation

5. Packaged in sterile conditions for research use

6. vilon 20mg peptide for research

: What is Vilon and how does it work in research?

A: Vilon is a synthetic dipeptide (Lys-Glu) that functions as a peptide bioregulator at the chromatin level . It promotes the unwrapping of facultative heterochromatin, reactivating genes silenced through age-related chromatin condensation, and supports immunomodulatory and geroprotective effects .

: What are the key research applications for Vilon?

A: Vilon is used in epigenetics and chromatin biology, immunology research (T-cell differentiation, cytokine regulation), aging and longevity studies, and gene expression profiling .

: What purity level can I expect?

A: All batches are tested to ensure ≥99% purity by HPLC analysis. Certificates of Analysis are available upon request .

: How should Vilon be stored?

A: Store lyophilized powder at -20°C in a sealed, desiccated container, protected from light and moisture. Vilon is hygroscopic, so careful handling is required to prevent moisture absorption .

: Is this product for human use?

A: No. Our Vilon is manufactured strictly for research use only (RUO). It is not intended for human consumption or clinical applications .vilon 20mg peptide for research

When you need premium vilon 20mg peptide for research for your chromatin biology, immunology, or aging studies, choose a manufacturer that prioritizes quality, transparency, and reliability. Liaocheng Yixin Company combines expert peptide synthesis capabilities with rigorous quality control to deliver research materials you can trust.